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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2bd70343f05e1b468cda814143606205b03111228429c4070a638b6b016561aa' 
  AND token = '3FydLEWFingcOuk1LAwEa9B17VgcKVP++iBDHKsH3IQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}