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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'bb1bd9914fae3c1644ee0e07dce2ca8fb20b88564462388c0cad27eee977b39c' 
  AND token = 'PVjG+NzPNp3TwQkWhraOKWWe5qkzN1O7BC0CmGQ5nD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}