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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'be27e78c798cb0ba8e815d0c8c029180c938e109a058a41c1f643ff599dd4c5f' 
  AND token = 'HqMHo9gBumijK5ypVjDOSTerebqlyeuT15Bast9TFuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}