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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '478315db715979e872cc7472b7297fe2b3a89914766dfeb58af3a3abf8b0dcf7' 
  AND token = 'b+zkwpn0qvi/GA52YjxuWuXuDR0DcxRcHudW2ep4MLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}