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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5afdb2d2bd35017854e5516dd5724202a7b23abc06e3391f1da2f6571cbd00fc' 
  AND token = 'z8AmQPGIQIneGWVK0iTNUoH4HOfxoDa95GwpYwvT3dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}