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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '74e5feb9002e2509f9352d13bb1a56fcac642eeee246f5881e1db60f5446dec4' 
  AND token = '3CJm/2nrCcIBMRG8McdxLaZlvPOSw53zBeOBSvm0inY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}