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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1e227bbbb9936c24984294cc079eba5401621a4dd445ce49b0c29805c8d71a51' 
  AND token = 'zzSw1eqKOI7IPA/e7nTwRj+B9z1fBzM3JTg0MMi9VEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}