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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2800d4ba620499bf23f368ca358a7691280d371898386d84f77054f26bc80ecf' 
  AND token = '0RIORcqMmNL8ax4re+AsFb7rm1kPb+uNR07v3fal/v4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}