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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '00410449ed2b1ebb6cc3af940334c0295c3e99d9bc8d981e81376f4f6617566e' 
  AND token = 'QVWSS/Eom/jVWHVdadiFygHuq/6894XxySzVC4kUIEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}