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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7c448b16415d1d4ccd43c64020f5b27c5d990f80f60e0f47a608ee8b9d81d2d7' 
  AND token = '4BmeFp/cvQVSBa9Y/FbITU2R7UZR2bWAl/lmRqPPcZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}