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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3207ecfb2157687378425a6f1659519aa4ca8279e4ad87a994adf89966f7f667' 
  AND token = 'wOJ0s6UD0mpyMf81C0k4raK2MG2ZqCyAIA4HSPna1Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}