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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e457088216a6d6fab76f8cbb3ff4605b44f1b5b5a842ea28b290ebcd49fccc66' 
  AND token = 'S9+wog4qZuYQCe2iieu278/CUZlz81OPRD5zxChLE1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}