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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c8720c9c8a30da09047c21478eedb92cf3a8976226d50c4fa2a65956b3f39365' 
  AND token = 'rB+cHRQ1Lt0h4L7am2enaxwswL9NnXiH+wlHSzjkrrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}