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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c77e2a0e2da3227f8e0990a7668d0071e9e4b654e36038603c1be2230ca05b27' 
  AND token = 'J7LrE1+zVPsqYA/n4DrZUkTRF1/bLRLeTqFBJeuo+xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}