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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4581021352f541346cc3bd7e213e89e13accda80b3bc1aa29f919a8838cc4569' 
  AND token = 'S6G/9IEroGb4F5tSISfsKL1KcNONOxmRHR3BtIlkvgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}