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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5fc3b2fa4aa6a7412e1e315f696b0121fca3b5d796272a829e99ae1214e2445c' 
  AND token = '2L4U1jlXctprhJVBtq4fRj9JYAW3fwx5vXCoTV24Z94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}