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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '765d80da40cc380dea9f46e2d4c2457e4c03b70ae041acb425775b1b989ea258' 
  AND token = 'XCm/32dFZYw52I631nocrguXcuZGpBIg/nBkCWms034=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}