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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f3f66848f6aabb9fd72b266baaf461c172421b99ede09863a3bdf29e556a4ae4' 
  AND token = 'VeiYEbGCQh4Lm5BtL+9+4d1VeyCYTOuz06mTeHYvtxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}