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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1899f242df2b79345020a2613622ae5a31ad6ede569561ae1b8fb3c8ab87c888' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}