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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ee748bb3544c9c2d4abc723a06e948d20291ebb65772dfe8243daa9b089e5581' 
  AND token = 'aT8Eeb3k5cptCw6fvGWTA5FS/yOQu6m5NQTLbVjJho4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}