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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b2978da7673661cf56dfb7d31db59183a5f175180150a2d8ad1cb01ff06b0367' 
  AND token = 'FPjH2oPn/IT5ga6jmvyNNnzt63MO2MU+rqLF+2hq/Uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}