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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '225d29606b0ef6fdd9a0a5508d0481af101eaec614f83a67fc4b467b3ae1c452' 
  AND token = 'Y3zkaS1jqoumdL3EfLWJJtFGCTySI0bWzoCBGVeG0JM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}