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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2c1c981dd08cbd6fe4858dcc03f2f518eb7028504b71ac2ba9443d9895bee3e5' 
  AND token = 'LS7QUUgAxyRYqWlrCHnM78urW86hPkAErPCru8NLaUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}