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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2c1663f5edb291c0852b8dd2c5142b9839b46b7572c208cc607239e5e04fb555' 
  AND token = 'QFP1b48X9Hii50M7SSH10v288/qLGJa0z/KtuIUG3aU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}