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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '28e3acd1d47fa38560f1824bd7d0021cf662fb0ff8a024fad0d753a35e811955' 
  AND token = 'eFBsdf76molLsCKhp0jvB7y2Oj4zpixegeeVHW2lhwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}