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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '14255870b08fa177d784604e8af9330e6c76b1a269fe46391034db585b6cbb4c' 
  AND token = 'kXoy9+9P1k0AfPWy5szpcmc/GYdF5buFS9VxxCBKpy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}