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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22801d098984bbd291d7d3738821e99496f99fa0d0fd724a9fc3bb2a66bb46b4' 
  AND token = 'DOQNFLtQYZg6b6uoil3csUX+fKl8jMIx99rh3gUm4KY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}