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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '468c18a058b34866e4505295343f3f9c92aace02b78959b9ec66b33e2106bd87' 
  AND token = '4o0S/IEQ46bJDItUPVRUEJm1/1nyO/agND9PF7y/GG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}