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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4fab876f7867641be083d4abac13512acd35d9f8cc8f36cb581a9893c1b4e843' 
  AND token = 'OEVXVKBGkVCE/rS19b+h67czdPoGnagVS8MEc1IAzFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}