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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'edfd3e37d65a81cbb2b17f7eafeb85b0ee8194784324fce5ed4f49a2f01dde6e' 
  AND token = '1o6EfTX6mFCbO0i4rtqmPj/EMBWPnPJmBe6Zah4rh2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}