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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5d018855b868e0bacb751d399899b281910edd2c9db1ffcb838d4c037f033443' 
  AND token = 'lxRJ7zOUNt81DzNErENXW9YHeIPR4wndeGY8AN2ello=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}