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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21a3c265edf55674b8ece90458c17154beb75740716747fa7584d17900be03fd' 
  AND token = 'tuplbj7ju8V75FkV9G0GV5DWDKRmSioEJjaYIQxBklw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}