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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2b804c03d5496c9e8c711f0f6753e53b34093cc364f6207df6cc24e2c2d7f016' 
  AND token = 'smom1imNOdLl5mC43hUSUKiWSd8QWYjW4KDNSGdy4UE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}