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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ac65ed16b4618741b21efe3ab53bfa6e3c0d935225d5fa0691cfa04178e04065' 
  AND token = '+AYI9RfH0fMV11Kzps4IhidnrfsMZ0li9krtY3ZQ3Lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}