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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7dfb90b08fcce61ab43e4578dd57e0a368c982afa9d7548aad376e1990a71bb2' 
  AND token = 'RJ0bHdN5EOIkPAr+6UDdHHrddVwTHiH8EpUaN1ZQMBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}