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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '728ba47e04491bb19cc2720e8677525b4c6e55f42fc87ff23185e0879af0cd48' 
  AND token = '0I+I0kp08KfUSK37/5Z51rFIlT9wBkcPdUoOckxUJ6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}