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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f2a0e6f1b09f440248d40eae8cab6c6439475a9479b3e30df3a5c1776d0814a3' 
  AND token = 'CCTefETKRSEM8X7Nkn+PNZsNbIM2uDwVJp2EeD5clJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}