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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd5a582f281af08228331e397694fb979a96fc949ef147e43abee09335c8e1c57' 
  AND token = 'Q/f+bjJg07gmJyHf3Jkq1p+NhE99LpfXlOi5Hn630wU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}