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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b2b95c610288369e21a506c395f1d5ef58469b7c49c77285e7fa63118d31a0e0' 
  AND token = 'JQPR/C/2Qhpnex1fzCXNDWj9MEMVtcSAe0X77R+/3Io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}