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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd2270e4f240ca158ca104a398d05c1b439b21085de406dc79379433d316b8eed' 
  AND token = 'sMOMonJB6c9NN2TV2TyCF7HDFkEyEsalxokhldBbWT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}