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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '79e3a91839931eeb0366eb3fbc2f9b7017ae7e1fd401111d2cf2f5f1548d2279' 
  AND token = 'k0HcctKazqe80dZVI9M6fZL30tkz58qnA061YGElYkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}