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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a8dfd0e3ff29bf29476eac42f4f8d3b2c52a1a68fb31b9446c48deb1de0f42dd' 
  AND token = 'XaOIuJ04/IQDA8YUpLq54jJdMGHsjDjm8FxbVU5PQLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}