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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '41bdaa1ec94244f50965b1839cd028a8498e8f3b0a99c1b22cf60e6258763ff3' 
  AND token = 'CY6cMfPbsdSH+stbUUaFoOC1YdglMweYgYQ5VDlLOfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}