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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4c62b0c4bb777fd18f3feb519f65eec47a81a116c594a1e4f504680ad870a234' 
  AND token = 'WH9n7YnKnMwSmw1ZUkIYcStw4fOZ+pT1vxjT9Y+Wv+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}