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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c9ceb6393bce0a128a35e6363678ca48c9b2a6944d9bd2052e1337d04d7f8795' 
  AND token = 'xSPa0/WsUwLs3NPPt4JWUKv1dM6QLP7x33c9phPkLWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}