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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2609eca2e27e8906f2f30f271de5276b59d6a47ec65a4692b179a9406db2b2fd' 
  AND token = 'ms4ioedEz4LHqPB4U/3fMZlR/AhX7v6SfLpf06nuwHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}