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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ea6e0c877988a4d25ab9223dedd1a567edf72b8fc98774dcde0007b0db11e519' 
  AND token = 'mw7K802cVcEd9IP+oR+/ZqZ6gGVJhW01qI6IM1UbiS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}