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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c34492723ac7861ee39ba2e142a3a3094a58ca5a8bde649b732e4e0a045b7211' 
  AND token = 'DTZng7yMDJq8xLOZcmYx5G/lobgYCsk9Y0/NsKhLE8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}