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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3298cb92e78c1b70fc895cb426235fe3fc9b06540a6d4a8be80aebcb7b1ff299' 
  AND token = 'M5f2bZKTQOSWM7uvd2QKbLqtXXfSzqJCOmnjqqivr3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}