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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '27e0c70ea7325bb8cc1fddb639a78d7e5aac7c4f42e00194dd3d9d5750e00a56' 
  AND token = '2AKnvoyt0WiyP4E2DpLL1eJaYQwDWLATHXUQ/27LE4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}